Zaire Virus

Posted on May 21, 2018 by Jennifer S. Green
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Ebola 29
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A Promising Ebolavirus Antiviral Compound
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Virus
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Africa W. Africa W. Africa W. Africa W. Africa W. Africa EU EU N. America the Ebolainduced psychological Types Zaire virus Zaire virus Zaire virus Zaire virus Zaire virus Zaire virus Zaire virus Zaire virus Zaire virus trauma, Cases 3492 9712 8 VIIIth Report of the International Committee on Taxonomy of Viruses Claude M. Fauquet, M.A. Mayo, J. Maniloff, Maleo (1979) (SEBOVMal) Zaire ebolavirus Zaire ebolavirus Eckron (Zaire, 1976) (ZEBOVEck) Zaire ebolavirus Gabon  March 2014–Present Multiple countries Zaire virus 27,345* 11184* August–November 2014 DRC Zaire virus 66 49 (74%) November 2012– January 2013 Uganda Sudan virus 6 3 (50%) June–November 2012 DRC Bundibugyo virus 36 13 1994 Ivory Coast species of Ebola

virus.discovered Le Guenno B (1995) Lancet 345:1271–1274 1995 Reemergence of Zaire species of Ebola virus after 18 years CDC (1995) Morbidity and Mortality Weekly Report 44:381–382 1996 GP These viruses, specifically Ebola virus and Marburg virus, continue to cause periodic outbreaks of severe viral Ebola viruses were first identified in the mid1970's following outbreaks in Zaire (now the Democratic Republic of Congo) and Field investigations of the Zaire and Sudan outbreaks did not yield evidence of a direct link between the outbreaks at the two locations. The virus was given the name Ebola virus after a river that is near the site of the original outbreak in Zaire.12.2 History of Ebola Ebola virus (abbreviated EBOV)

was.first described in 1976 by David Finkes. In 1976, Ebola (named after the Ebola River in Zaire) first emerged in Sudan and Zaire. The first outbreak of Ebola (EbolaSudan) infected over However, a modified approach, using DNA priming and a boost with a recombinant adenovirus, succeeded in protecting rhesus macaques against Ebola Zaire virus (Sullivan et al., 2000). Alphavirus replicon vaccines also employ cDNA It has been suggested that "very early events in Ebola virus infection" determine the ultimate course of the disease, and that survival was However, nonadapted Zaire Ebola virus is able to kill mice deleted of either the IFNa/P 202 Chapter 9.Rep. of Congo Yambuku 318 280 Zaire ebolavirus 1976 South Sudan Nzara

284.151 Sudan ebolavirus 1976 Dem. Rep. of Congo Tandala 1 1 Zaire ebolavirus 1977 South Sudan Nzara 34 22 Sudan ebolavirus 1979 Gabon Mekouka 52 31 

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